ea0011p599 | Neuroendocrinology and behaviour | ECE2006
Picu A
, Giordano R
, Bonelli L
, Balbo M
, Pellegrino M
, Berardelli R
, Corneli G
, Gasco V
, Ghigo E
, Arvat E
Insulin tolerance test (ITT) is considered the golden standard test to evaluate HPA axis in suspected hypopituitarism. Low dose (1 μg) ACTH124 short stimulation test (LDSST) and metyrapone are often used when ITT is contraindicated. The diagnostic reliability of LDSST is, however, controversial, as even this dose has been considered supramaximal, while very low ACTH doses have been suggested more reliable to assess the adrenal sensitivity. Thus, in...